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E from the study of the effect of brefeldin A (BFA) on tobacco BY-2 cells (Ritzenthaler et al., 2002). BFA is a fungal toxin that inhibits the activity of guanine nucleotide exchange factor of the Arf GTPases and thus inhibits the membrane recruitment of coatomer and the formation of COPI vesicles4290 | C. H. Woo, C. Gao, et al.(Donaldson et al., 1992). BFA treatment causes a rapid loss of coatome
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